![]() ![]() Studies show that discontinuation of inhaled steroids restores the voice in dysphonic patients, but symptoms may not resolve immediatelyĭiuretics have a drying effect on mucous membranes, including those used to speaking and singing. ![]() The onset of symptoms and severity of symptoms is highly variable among patients. Patients using inhaled steroids sometimes experience voice changes (including complete loss of voice). Unfortunately, there may be no early warning signs noticeable signs and symptoms like hoarseness, difficulty swallowing, or throat lumps often don’t appear until the tumor has advanced. The earlier medullary thyroid cancer is found, the more likely it can be stopped and treated. However, exenatide extended-release is contraindicated in patients with a personal or family history of medullary thyroid cancer and in patients with Multiple Endocrine Neoplasia syndrome. It is unknown whether this is true for humans. Glucagon-like peptide-1 for diabetes mellitus 2Įxenatide extended-release causes an increased incidence in thyroid C-cell tumors at clinically relevant exposures in rats compared to controls. ![]() Additionally, dry vocal tissues may be more prone to injuries such as nodules. The specific events reported are acid regurgitation (4.1%) including pyrosis (heartburn), flatulence (4.1%), gastroesophageal reflux disease (GERD) (0.7%), dyspepsia (3.4%), diarrhea (1.4%), abdominal pain (2.1%), and nausea (2.1% ).Īdderall may have a drying effect on vocal fold tissues, which can lead to hoarseness, soreness, voice changes and laryngitis. Uncontrolled acidic spillage of stomach acids into the larynx is harmful to delicate vocal fold tissues.Īdverse effects with oral risedronate during the clinical trials were reported as generally mild and primarily affected the gastrointestinal system. These agents have a favorable effect on the voice in that they reduce damage of gastrointestinal reflux (GERD). The mucocutaneous drying effects of isotretinoin are dose-related and are usually reversible following discontinuation. Other mucocutaneous effects frequently encountered include xerosis, xerostomia, epistaxis, peeling, and pruritus. Cheilitis (inflammation of the lips) occurs in more than 90% of patients and appears to be dose-related. No effects on voice or speech mechanisms have been reported.Īntihistamine-leukotriene receptor antagonistĮxcessive coughing has been associated with the use of ACE inhibitors, which in turn, may lead to hoarseness and possibly vocal tissue damage.Īdverse mucocutaneous effects are frequently reported with isotretinoin. ![]()
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